PERIBOSTON

PERIBOSTON

202105-0202 • 3141 Views •  Box of 10 blisters x 10 tablets.

COMPOSITION

Each tablet contains:

Active ingredient:

Cyproheptadin hydrocloride 4 mg

 

In allergy and pruritus: Cyproheptadine Hydrochloride has a wide range of anti-allergic and antipruritic activity, and can be used successfully in the treatment of acute and chronic allergic and pruritic conditions, such as dermatitis, including neurodermatitis and neurodermatitis circumscripta; eczema; eczematoid dermatitis; dermatographism; mild, local allergic reactions to insect bites; hay fever and other seasonal rhinitis; perennial allergic and vasomotor rhinitis; allergic conjunctivitis due to inhalant allergens and foods; urticaria; angioneurotic oedema; drug and serum reactions; anogenital pruritus; pruritus of chicken pox.

In migraine and vascular headache: The characteristic headache and feeling of malaise may disappear within an hour or two of the first 4 mg dose

 

- POSOLOGY AND METHOD OF ADMINISTRATION

Posology

For the treatment of allergy and pruritus:

Dosage must be determined on an individual basis. The effect of a single dose usually lasts for four to six hours. For continuous effective relief, the daily requirement should be given in divided doses, usually three times a day.

Adults: The therapeutic range is 4-20 mg a day, most patients requiring 12-16 mg a day. It is recommended that dosage be initiated with 4 mg three times a day and then adjusted according to the weight and response of the patient up to a maximum of 32 mg a day.

Children aged 7-14 years: Usually 4 mg two or three times a day, according to the patient's weight and response. If an additional dose is required, it should be given at bedtime. Maximum 16 mg a day.

Children aged 2-6 years: Initially 2 mg two or three times a day, adjusted according to the patient's weight and response. If an additional dose is required, it should be given at bedtime. Maximum 12 mg a day.

For treatment of vascular headache and migraine

For both prophylactic and therapeutic use, an initial dose of 4 mg, repeated, if necessary, after half an hour. Patients who respond usually obtain relief with 8 mg, and this dose should not be exceeded within a 4- to 6-hour period.

Maintenance: 4 mg every four to six hours.

Use in the elderly: Cyproheptadine Hydrochloride should not be used in elderly, debilitated patients. Elderly patients are more likely to experience dizziness, sedation, and hypotension.

Administration

For oral administration only

There is no recommended dosage for children under 2 years old, elderly and debilitated patients

- CONTRAINDICATIONS

Cyproheptadine Hydrochloride is contraindicated in:

• patients undergoing therapy for an acute asthmatic attack; 

• pregnancy and breast-feeding mothers; 

• patients with known sensitivity to cyproheptadine hydrochloride or drugs with similar chemical structure; 

• concurrent use with monoamine oxidase inhibitors (IMAO);

• glaucoma;

• patients with a history of agranulocytosis

• patients with stenosing peptic ulcer, 

• patients with pyloroduodenal obstruction, 

• patients with symptomatic prostatic hypertrophy, 

• patients with bladder neck obstruction;

• elderly, debilitated patients.

- WARNINGS AND PRECAUTIONS

Antihistamines should not be used to treat lower respiratory tract symptoms, including those of acute asthma. 

The safety and efficacy of Cyproheptadine is not established in children under 2 years old.

Overdosage of antihistamines, particularly in infants and children, may produce hallucinations, central nervous system depression, convulsions, respiratory and cardiac arrest, and death. 

Antihistamines may diminish mental alertness; conversely, particularly in the young child, they may occasionally produce excitation

Patients should be warned against engaging in activities requiring motor co-ordination and mental alertness, such as driving a car or operating machinery 

Prolonged therapy with antihistamines may cause blood dyscrasias

Because Cyproheptadine has an atropine-like action, it should be used cautiously in patients with a history of bronchial asthma, increased intra-ocular pressure, hyperthyroidism, cardiovascular disease, or hypertension

Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.

- Shelf-life

36 months from the manufacturing date. Do not use after the expiry date

Al/PVC blister. Box of 03 blisters x 10 tablets.

Al/PVC blister. Box of 05 blisters x 10 tablets.

Al/PVC blister. Box of 10 blisters x 10 tablets.

 

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