Oflo-Boston

Oflo-Boston

201912-0027 • 9282 Views • Box of 10 blisters x 10 film-coated tablets
COMPOSITION

Each film-coated tablet contains:

Active ingredient                                           

Ofloxacin 200 mg

 

Infections caused by susceptible bacteria in diseases : 

- Skin and soft tissue infections.

-  Colitis caused by infection.

- Chlamydia trachomatis infection of the urethra and/or cervix with or without gonorrhea, uncomplicated gonorrhea, prostatitis.

- Complicated urinary tract infections.

- Pneumonia. 

Because fluoroquinolones antibiotics, including ofloxacin, have been associated with serious adverse reactions (see Warnings) and infections in some patients may resolve on their own, such as: uncomplicated urinary tract infections, acute exacerbation of chronic bronchitis; treatment of these patients with ofloxacin should only be initiated in the absence of alternative treatment options.

 

Method of administration: Oflo-Boston is oral use, the rate of absorption is not affected by food.

Dosage:

Adults

Skin and soft tissue infections: 400 mg orally every 12 hours/time, for 10 days.

Pneumonia: 400 mg orally every 12 hours/time, for 10 days.

Chlamydia infection (in the cervix and ureters): 300 mg orally every 12 hours/time for 7 days.

Gonorrhea, uncomplicated: Oral 400 mg, a single dose.

Complicated urinary tract infections: 200 mg orally every 12 hours/time for 10 days.

Uncomplicated urinary tract infections: 200 mg orally every 12 hours/time for 3-7 days.

Adults with impaired renal function:

Creatinine clearance > 50 ml/min:  Dose unchanged, taken every 12 hours.

Creatinine clearance 10 - 50 ml/min: Dose unchanged, taken every 24 hours.

Creatinine clearance < 10 ml/min: Take half a dose, every 24 hours/time.

Children under 18 years old: Do not use Ofloxacin.

CONTRAINDICATIONS

Hypersensitivity to ofloxacin or any of the excipients.

Children under 18 years old, pregnant or breastfeeding women.

WARNINGS AND PRECAUTIONS 

Disabling and potentially irreversible serious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy and central nervous system adverse effects. 

Fluoroquinolone antibiotics have been associated with disabling and potentially irreversible serious adverse reactions from different body systems that can occur together in the same patient.  Adverse reactions reported include tendinitis, tendon rupture, arthralgia, myalgia, peripheral neuropathy, and central nervous system effects (hallucinations, anxiety, depression, insomnia, severe headaches, and confusion). These reactions can occur within hours to weeks after starting ofloxacin.  Patients of any age or without pre-existing risk factors have experienced these adverse reactions.

Treatment should be discontinued immediately at the first signs or symptoms of any serious adverse reaction.  In addition, avoid the use of fluoroquinolones, including ofloxacin, in patients who have experienced any of these serious adverse reactions associated with fluoroquinolones.

Use with caution in patients with epilepsy or a history of central nervous system disorders, in patients with impaired liver function or renal function.

The treatment with ofloxacin should be discontinued and tell your doctor if the patient experiences symptoms of tendon pain, tendinitis, or tendon rupture.

Avoid exposure to light while taking the drug. Treatment discontinuation if symptoms of photosensitization.

Like other quinolones, ofloxacin can cause life-threatening hypersensitivity reactions at the start of treatment.  Treatment should be discontinued and tell your doctor if you develop a rash, urticaria, other skin reactions, or any symptoms of a hypersensitivity reaction. 

As with other antibiotics, ofloxacin may result in the overgrowth of non-susceptible organisms. Therefore, patients should be carefully monitored and periodic susceptibility tests of the bacteria should be performed.

Special caution should be exercised in Clostridium difficile colitis, treatment with ofloxacin should be discontinued if it is being used.

SHELF-LIFE 

36 months from the manufacturing date. Do not use after the expiry date.

 

Box of 10 blisters x 10 film-coated tablets
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