EFFER-PARALMAX 250

DOSAGE AND ADMINISTRATION

EFFER-PARALMAX 250 is administered orally, dissolve the drug with sufficient water, take after dissolved drug completely, dose interal should are not less than four hours.

Do not give more than 5 doses in 24 hours to reduce pain and fever.

Dose can usually be used:

    + Children 1 to 2 years    :    120 mg paracetamol/time (720 mg powder/time).

    + Children 2 to 3 years    :    160 mg paracetamol/time (960 mg powder/time).

    + Children 4 to 5 years    :    1 sachet/time.

    + Children 6 to 8 years    :    320 mg paracetamol/time (1920 mg powder/time).

    + Children 9 to 10 years    :    400 mg paracetamol/time (2400 mg powder/time).

Or use your physicians’s prescription.

Note: Do not be extended using paracetamol for self-treatment in children when:

    + Symptoms of pain has extended longer than 5 days.

    + Symptoms of high fever (above 39.5°C) has extended longer than 3 days.

    + More severe diseases or other symptoms appear.

CONTRAINDICATIONS

Hypersensitivity to paracetamol or to the excipients.

Patients with severe hepatic impairment.

Patients with G6PD enzyme deficiency.

Patients with anemia, patients with severe renal impairment

WARNINGS AND PRECAUTIONS

Patients should be advised that paracetamol may cause severe skin reactions. If a skin reaction such as skin reddening, blisters, or rash occur, they should stop use and seek medical assistance right away.

Thrombocytopenia, leukopenia, reducing whole blood were occurred when use  the p-aminophenol derivatives, especially use the prolongation of large dose.  Decreasing neutrophil and hemorrhage have been reported after using paracetamol. Agranulocytosis was happened.

Caution for patients with anemia.

Drink alcohol too much and using paracetamol for long time may increase the risk of liver toxicity, should avoid using alcohol.

Care is advised in the administration of paracetamol to patients with severe renal or severe hepatic impairment.

Do not take with any other products containing paracetamol.

This medicinal product contains sorbitol. Patients with rare hereditary problems of fructose intolerance should not take this medicine.

Doctor should warn the patients about  the signs of serious skin side-effects such as Steven-Johnson syndrome (SJS), toxic epidermal necrolysic (TEN) or Lyell syndrome, acute generalized exanthematous pustulosis (AGEP)

PREGNANCY AND LACTATION

Pregnancy: Epidemiological studies in human pregnancy have shown no ill effects due to paracetamol used in the recommended dosage, but patients should follow the advice of the doctor regarding its use.

Lactation: Paracetamol is excreted in breast milk but not in a clinically significant amount. Available published data do not contraindicate breast feeding

STORAGE CONDITION

In a dry place, below 30°C, protect from light.

SHELF-LIFE 

36 months from the manufacturing date.