BOSAGAS 80

DOSAGE AND ADMINISTRATION

Administration: Telmisartan tablets are for once-daily oral administration and should be taken, with or without food.

Dosage

Adults: 40 mg once daily. Some patients may already benefit at a daily dose of 20 mg. The dose of telmisartan can be increased to a maximum of 80 mg once daily if needed. Alternatively, telmisartan may be used in combination with thiazide-type diuretics. When considering raising the dose, it must be borne in mind that the maximum antihypertensive effect is generally attained four to eight weeks after the start of treatment.

Renal impairment: No dose adjustment is necessary for patients with renal impairment.

Hepatic impairment: In patients with mild to moderate hepatic impairment, the posology should not exceed 40 mg once daily 

Elderly: No dose adjustment is necessary for elderly.

Children: The safety and efficacy of Telmisartan in children and adolescents aged below 18 years have not been established.

CONTRAINDICATIONS

Hypersensitivity to any of the excipients.

Pregnancy and lactation.

Severe renal impairment

Severe hepatic impairment. Biliary obstructive disorders

WARNINGS AND PRECAUTIONS

Monitoring of serum potassium is recommended, especially in the elderly and in patients with renal impairment. Reduce the starting dose in these patients.

Aortic and mitral valve stenosis. 

Obstructive hypertrophic cardiomyopathy

Severe congestive heart failure.

Intravascular hypovolemia (volume and sodium depleted by vomiting, diarrhoea, long term diuretic therapy, haemodialysis, dietary salt restriction) may increase the risk of symptomatic hypotension. 

Such conditions should be corrected before the administration of telmisartan or reduced dose and closely monitored while administration.

Active gastric ulcer disease or other gastrointestinal disorders

Mild to moderate hepatic impairment

Renal artery stenosis.

Mild to moderate renal impairment

When driving vehicles or operating machinery it should be taken into account that dizziness or drowsiness may occasionally occur when taking antihypertensive therapy such as telmisartan.

SHELF-LIFE 

36 months from the manufacturing date.