Each hard capsule contains:
Active ingredients:
Fenofibrate | 300 mg |
Treatment of disorders of lipoproteinanemia in types IIa, IIb, III, IV and V, in combination with diet.
POSOLOGY, METHOD OF ADMINISTRATION
Method of administration: Combine treatment with a fat-lowering diet. The drug should be taken with meals to maximize bioavailability.
Posology:
Adults: Take 1 capsule/day; take 1 time with the main meal.
The initial dose of fenofibrate is usually 200 mg/day (once or twice); if total cholesterolemia is still higher than 4 g/l, the dose can be increased to 300 mg/day. The initial dose should be maintained until cholesterolemia returns to normal after the daily dose can be slightly reduced. Cholesterolemia must be checked every 3 months; if blood lipid parameters increase again, the dose must be increased to 300mg/day.
CONTRAINDICATIONS
Hypersensitivity to any of the ingredients of the drug.
Patients with renal impairment
Severe liver dysfunction.
It's not suitable for children.
Pregnancy and lactation
WARNINGS AND PRECAUTIONS
- It is essential to assess the patient's liver and kidney function before treatment with fenofibrate.
- When initiating fibrate in a patient taking anticoagulants, the anticoagulant dose should be reduced to only one-third of the original dose and adjusted if necessary—more frequent monitoring of blood prothrombin levels. Adjust anticoagulant dose during use and 8 days after stopping fibrate.
- If after 3 - 6 months of treatment with the maximum recommended daily dose, lipidaemias do not decrease, an additional or alternative treatment must be considered.
- Do not combine fenofibrate with drugs that have hepatotoxic effects.
- Complications of cholelithiasis are more likely to occur in people with cholestatic cirrhosis or gallstones.
- Fenofibrate is not recommended for children below 18 years of age, as the safety and effectiveness were not established.
- It is recommended that transaminase levels be monitored every 3 months during the first 12 months of treatment. Fenofibrate therapy should be discontinued if SGPT (ALT) > 100 UI.
SHELF-LIFE
36 months from the date of manufacture. Do not use the products over the expiry date.
5 blisters x 10 hard capsules