Ciprom 500

Method of administration:

For oral use only, if you want the drug to be absorbed quickly, you should take it 2 hours after eating. Take medicine with plenty of water and do not take anti-acid stomach medicine after taking it

Posology: 

Adults: 500 mg/time x 2 time/ day

Anthrax: Adults 500 mg/time x 2 time/ day

Prophylaxis of meningococcal diseases:

+ Adults and children > 20 kg: 500 mg, only one dose.

+ Childrent < 20 kg: 250 mg, oly one dose or 20 mg/ kg

The duration of ciprofloxacin treatment depends on the type of infection and the severity of the disease and should be determined according to the patient's clinical and microbiological response. For most infections, treatment should continue for at least 48 hours after the patient is symptom-free. Duration of treatment is usually 1 - 2 weeks, but with severe infections or complications, longer treatment may be required. Treatment with ciprofloxacin may need to be continued for 4-6 weeks or longer in bone and joint infections. Infectious diarrhea usually takes 3-7 days or less

Dose reduction is required in patients with impaired renal or hepatic function. In the case of people with impaired kidney function, if the dose is low, it is not necessary to reduce the dose; If high doses are used, the dose should be adjusted based on creatinine clearance, or serum creatinine concentration.

Creatinine clearance

31 – 60 (serum creatinine: 120-170 micromol/ liter): Dose ≥ 750 mg x 2 time, reduced 500 mg x 2 time/day

≤ 30 (serum creatinine:> 175 micromol/ liter) Dose ≥ 500 mg x 2 time, reduced 500 mg x 1 time/day

Contraindications

People with a history of hypersensitivity to ciprofloxacin and related drugs such as nalidixic acid and other quinolones

Do not use the drug for pregnant and lactating women, unless absolutely unless necessary

Warnings and precaution

Serious potentially irreversible and disabling adverse reactions, including tendinitis, tendon rupture, peripheral neuropathy, and central nervous system adverse effects

-Fluoroquinolone antibiotics have been associated with potentially fatal and irreversible adverse reactions in various body systems. These reactions may occur simultaneously in the same patient. Commonly reported adverse reactions include to tendinitis, tendon rupture, arthralgia, myalgia, peripheral neuropathy, and central nervous system adverse effects (hallucinations, anxiety, depression). , insomnia, severe headache, and confusion). These reactions can occur within hours to weeks of taking the drug. Patients of any age or without pre-existing risk factors may experience these adverse reactions.

-Discontinue use at the first sign or symptom of any serious adverse reaction. In addition, avoid the use of fluoroquinolone antibiotics in patients who have experienced serious fluoroquinolone-related reactions

-Caution should be exercised when using ciprofloxacin in patients with a history of seizures or central nervous system disorders, patients with impaired liver or kidney function, G6PD deficiency, and muscle weakness.

-Long-term use of ciprofloxacin may cause an overgrowth of bacteria that are not sensitive to the drug. It is imperative to monitor the patient and make regular antibiotic charts to take appropriate treatment according to the antibiotic chart

-Ciprofloxacin can cause tests for Mycobacterium tuberculosis to be negative

-Ciprofloxacin can cause dizziness, and lightheadedness, and affect the ability to drive or operate machinery.

-Limit the use of drugs for children and growing children

 Shelf life

months from the manufacturing date. Do not use it  after the expiry date.

Box 05 blister x 10 film -coated tablet