Piroton 800

POSOLOGY, METHOD OF ADMINISTRATION

Method of administration: For oral use.

Usual dose for adults: 1.8 g - 2.4 g / day, depending on indications, divided in two or three doses. Divided in  2 or 3-4 doses.

Usual dose for children: 50 mg/kg/day, divided into 3 times.

Long term treatment for psycho-organic syndroms in the elderly: 1.2 -2.4 g daily, depending on the case. The dose can be as high as 4.8 g daily during the initial weeks of therapy.

Treatment of alcoholism: 12 g/day during the initial withdrawal period. Maintenance treatment: 2.4 g/day

Cognitive deficits resulting from head injury: the initial dose is 9-12 g daily; the maintenance dose is 2.4 g given orally for a period of not less than 3 weeks.

Sickle-cell anemia: 160 mg/kg daily, divided in 4 equal doses.

Cortical myoclonus, a recommended protocol would be to begin treatment with 7.2 g of piracetam daily in 2-3 divided doses. This dosage should be increased by 4.8 g per day, every 3 or 4 days until obtaining a satisfactory response or a maximum dose of 20 g daily.

Dosage should be reduced in patients with mild to moderate renal impairment based on creatinine clearance (CC): 

CC from 50 - 79 ml/min: 2/3 usual daily dose, divided in 2 or 3 doses 

CC from 30 - 49 ml/min: 1/3 usual daily dose, divided in 2 doses

CC from 20 - 29 ml/min: 1/6 usual daily dose, 1 single intake 

Patients with severe renal impairment (creatinine clearance of less than 20 ml/min): should not be used.

CONTRAINDICATIONS

Severe renal impairment

Pregnancy and lactation

Patients suffering from Huntington's Chorea

Patients with hepatic impairment

WARNINGS AND PRECAUTIONS

Piracetam is eliminated via the kidneys and care should thus be taken in cases of renal insufficiency.

For patients with hemodynamic disorders, major surgery or severe bleeding because Piracetam affects platelet activation.

Shelf life

36 months from date of manufacture. Do not use the products over the expiry date.

PIROTON 400: Box of 5 blisters x 10 hard capsules. 

PIROTON 600: Box of 5 blisters x 10 film-coated tablets. 

PIROTON 800: Box of 5 blisters x 10 film-coated tablets.