Irbetan 150

POSOLOGY AND METHOD OF ADMINISTRATION

Method of administration: 

IRBETAN 150 is for oral use, it may be taken with food.

Posology

The initial dose is 1 tablet once a day, the dose of irbesartan can be increased to 2 tablets and other antihypertensive agents can be added.

No dosage adjustment is necessary in patients with renal impairment. A starting 75 mg dose should be considered for patients undergoing haemodialysis.

Before taking irbesartan, it is necessary to correct hypovolemia, dehydration, and salt loss. 

Initiation of therapy with 75 mg could be considered, particularly in hypovolemia patients and in the elderly over 75 years. Irbesartan is not recommended for children aged 6 – 16 years. For children with chronic kidney disease, the starting dose is 37.5 mg per day (children weighing 10 to 20 kg), 75 mg per day (children weighing 21-40 kg) and 150 mg per day (children weighing more than 40 kg); it could double the dose if response is inadequate.

CONTRAINDICATIONS

Hypersensitivity to irbesartan or to any of the excipients of this medicine

Pregnancy.

Breast-feeding

WARNINGS AND PRECAUTIONS

Care should be taken when administering the drug to patients with: hypovolemia, renal artery stenosis, renal transplantation or renal failure, hyperkalemia, primary hyperaldosteronism, aortic stenosis, mitral valve stenosis, obstructive hypertrophic cardiomyopathy, severe congestive heart failure, patients with severe congestive heart failure or renal disease.

The risk of sudden and strong hypotension can easily cause myocardial infarction or cerebrovascular accident.

Shelf-life

36 months from the manufacturing date. Do not use after the expiry date

Box of 5 blisters x 14 film coated tablet.